The following are questions that are often asked about BEXSERO and meningococcal disease caused by Neisseria meningitidis group B strains (meningitis B). Just tap the question to read the answer. If you have additional questions, please speak with your doctor.

Who should get vaccinated with BEXSERO?

BEXSERO can be given to individuals from 2 months through 25 years of age to help protect against meningococcal disease caused by Neisseria meningitidis group B strains (meningitis B).

BEXSERO is not expected to protect against all circulating meningococcal B strains and does not offer protection against strains A, C, Y, and W-135. As with any vaccine, BEXSERO may not fully protect all of those who are vaccinated.

When should BEXSERO not be used?

BEXSERO should not be used if your child is allergic (hypersensitive) to the active substances or any of the other ingredients of BEXSERO.

Medicinal ingredients in BEXSERO

The active substances are:

50 μg of recombinant Neisseria meningitidis group B NHBA fusion protein

50 μg of recombinant Neisseria meningitidis group B NadA protein

50 μg of recombinant Neisseria meningitidis group B fHbp fusion protein

25 μg of Outer Membrane Vesicles Neisseria meningitidis group B strain NZ98/254

Antigens are adsorbed on aluminum hydroxide (0.5 mg aluminum).

Non-medicinal ingredients in BEXSERO

The important non-medicinal ingredients are:

Sodium chloride, histidine, sucrose, water for injections.

Talk to your doctor, pharmacist, or nurse for additional information.

How is BEXSERO administered and how often?

The doctor, pharmacist or nurse will inject BEXSERO into your child’s arm or leg muscle, depending on age.

Recommended vaccination schedule:

Age group at time of first dose

Infants (Option 1)

2 through 5 months of age

Primary immunization

Primary doses

Each dose is 0.5 mL

2

Interval between primary doses

≥2 months

Booster dose

(0.5 mL)

1 dose

required in the 2nd year of life after an interval of ≥6 months from the last injection of the initial course.

Infants (Option 2)

2 through 5 months of age

Primary immunization

Primary doses

Each dose is 0.5 mL

3

Interval between primary doses

≥1 month

Booster dose

(0.5 mL)

1 dose

required in the 2nd year of life after an interval of ≥6 months from the last injection of the initial course.

Infants

6 through 11 months of age

Primary immunization

Primary doses

Each dose is 0.5 mL

2

Interval between primary doses

≥2 months

Booster dose

(0.5 mL)

1 dose

required in the 2nd year of life, after an interval of ≥2 months from the last dose. The need for further doses has not been established.

Children

12 months through 23 months

Primary immunization

Primary doses

Each dose is 0.5 mL

2

Interval between primary doses

≥2 months

Booster dose

(0.5 mL)

Need not established.

Children

2 years through 10 years of age

Primary immunization

Primary doses

Each dose is 0.5 mL

2

Interval between primary doses

≥1 month

Booster dose

(0.5 mL)

Need not established.

Adolescents and adults

11 through 25 years of age

Primary immunization

Primary doses

Each dose is 0.5 mL

2

Interval between primary doses

≥1 month

Booster dose

(0.5 mL)

Need not established.

To download this dosing schedule click on the button below.

Download this schedule

What if a dose is missed?

If you forget to go back to the doctor/pharmacist/nurse at the scheduled time ask the doctor/pharmacist/nurse for advice.

Don’t forget to sign up for the BEXSERO dose reminder tool that will let you know when your child’s next dose is due.

Where is BEXSERO administered?

BEXSERO will be injected into your child’s arm or leg muscle, depending on age.

Talk to your doctor, pharmacist, or nurse for further information.

Make sure that your child gets all of the required doses. This allows your child to get the full benefits of BEXSERO.

Can BEXSERO be given with other vaccines?

BEXSERO can be given at the same time as any of the following vaccine antigens, either as single or as combination vaccines:

  • Diphtheria
  • Tetanus
  • Acellular pertussis (whooping cough)
  • Haemophilus influenzae type b
  • Inactivated polio
  • Hepatitis B
  • Heptavalent pneumococcal conjugate
  • Measles
  • Mumps
  • Rubella
  • Chickenpox
  • Meningococcus C

When BEXSERO is given at the same time as any of the vaccines listed above, the vaccines must be given at separate sites.

Talk to your doctor, pharmacist, or nurse for further information.

Is the cost of BEXSERO covered?

The cost of BEXSERO may be covered by your private insurance.

Contact your insurance provider and give the DIN
(drug identification number) below to find out.

BEXSERO DIN: 02417030

What is meningococcal disease and what causes it?

Meningococcal disease is a rare but potentially life-threatening bacterial infection caused by different strains of Neisseria meningitidis also known as meningococcus bacteria.

In Canada, invasive meningococcal disease (IMD) is most commonly associated with Neisseria meningitidis (meningococcus bacteria) strains A, B, C, W-135, and Y.* Meningitis B was the leading cause of meningococcal disease in Canada from 2003 through 2011.

Meningococcus bacteria include Neisseria meningitidis group B strains (meningitis B).

Meningitis B* was the leading cause of invasive meningococcal disease in Canada from 2011-2015.

The most common forms of the meningococcal disease include:

  • Meningitis (infection of the lining of the brain and spinal cord).
  • Sepsis (blood poisoning).

Up to 1 in 10 patients die
(typically within 24 to 48 hours after the onset of symptoms)

Of those who recover, up to 1 in 3 patients experience serious complications, including hearing loss, neurologic disabilities and amputations

* BEXSERO is not expected to provide protection against all circulating meningococcal serogroup B strains and does not offer protection against strains A, C, Y, and W-135.

† BEXSERO does not treat or reduce the consequences of meningococcal meningitis, including meningitis, sepsis, and death.

Who is at risk?

Between 2006 and 2011, the highest incidence of IMD was in infants under 1 year of age, then children under 5 years of age, and then adolescents 15 to 19 years of age.*

Up to 10% of healthy people are carriers of the infection and may remain carriers for up to 6 months without any symptoms.

The infection is transmitted from an infected person (including carriers) to another person through close, direct contact such as kissing, coughing and sneezing.

Contact may occur at daycare, school, university, or social situations such as team sports. In fact, the germs that cause meningococcal disease can be carried and spread by people who might not be showing symptoms.

* BEXSERO is indicated for individuals 2 months through 25 years of age.

How does meningococcal disease spread?

The bacteria that cause meningococcal disease (including meningitis and sepsis) may spread through close contact with other people.

The germs that cause meningococcal disease may be carried and spread by people who are not showing any symptoms.

  • An individual infected with meningococcal bacteria can spread the disease up to 7 days before showing symptoms of meningococcal disease.
  • Up to 1 in 10 healthy people are carriers of the infection and may remain a carrier for up to 6 months without any symptoms.

Like the common cold, meningococcal bacteria may be transmitted by direct contact with secretions from the nose and throat.

Everyday and sociable activities may spread meningococcal bacteria from person to person and may include:

Coughing and sneezing

Kissing

Sharing eating utensils and drinking glasses

Close physical contact

Because preventing the spread of germs—especially among children and adolescents—is nearly impossible, vaccination becomes an important consideration.

What are the symptoms of meningococcal disease?

Symptoms begin mildly like a cold or flu (e.g., fever, headache, aches and pains in joints and muscles)

Up to 1 in 10 patients die (typically within 24 to 48 hours after the onset of symptoms)*

Of those who recover, up to 1 in 3 patients experience serious complications, including hearing loss, neurologic disabilities and amputations*

How can I protect my child against meningococcal disease?

Prevention is the best strategy for combating any infectious disease…including meningococcal disease.

Consider vaccination with BEXSERO to help protect individuals 2 months through 25 years against meningococcal disease caused by Neisseria meningitidis group B strains (meningitis B).

Talk to your doctor about BEXSERO, the first and only meningitis B vaccine that can be used in children under 10 years of age. BEXSERO is indicated for individuals from 2 months through 25 years of age, to help protect against disease caused by Neisseria meningitidis group B strains (meningitis B).